An advanced presentation of toxicology in the occupational environment. Analysis of target organs, adverse health effects, and the systems/organs that are the targets of toxicants. Includes assessments of safety and risk of carcinogenic and non-carcinogenic chemicals.
- Compare and discriminate between the major sub-disciplines of toxicology and their roles in occupational safety and health.
- Illustrate the mechanisms by which a toxicant passes through the cell membrane: routes of absorption, the distribution process, and routes of excretion of a toxicant.
- Summarize and compare three types of Phase I reactions and the most common types of Phase II reactions.
- Classify sub-cellular sites of action, types of molecular targets, and types of receptors that are responsible for being mediators of effects of toxins.
- Compare and discriminate the different mechanisms of action that a toxin can use and the effects of chemical interactions among toxins.
- Compare and discriminate the differences and similarities between chemical carcinogenesis, mutagenesis, and teratogenesis.
- Summarize toxicants in human breast milk and adverse infant effects.
- Discriminate common examples of toxins that affect the following systems or target organs in the human body: immune, respiratory, liver, kidney, skin, eye, nervous system, reproductive, and cardiovascular.
- Describe the major toxicological concern of food additives, food contaminants, insecticides, metals, and over-the-counter drugs on human health.
- Summarize the toxic effects of common organic solvents, air pollutants, and water and soil pollutants.
- Discriminate the toxic substances at workplaces and their toxic effects.
- Explain the risk assessment procedures for non-carcinogenic and carcinogenic chemicals.
- BIO 1100
- CHM 1030
Principles of toxicology: Environmental and industrial applications (Rev: 3rd ed.)
Publisher: Wiley (2015)
Author: Roberts, S. M., James, R. C., & Williams, P. L. (Eds.).
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